Istiklal Avenue is one of the most remarked streets in the heart of Istanbul, Turkey, situated in the Pera district. The location serves as a blend of late Ottoman architecture and encompassing modern tourist attractions, spanning from the Genoese neighbourhood up to Taksim Square, centred by Galatasaray Square. Istiklal Avenue offers historical and contemporary significance, attracting millions of visitors on a nearly daily basis.

The most popular activities along Istiklal Avenue include partaking in plentiful shopping opportunities, visiting historic cinemas such as Atlas, touring the churches of St Antoine and Santa Maria, and sightseeing among the busy crowds. Other attractions include a range of dining options, libraries, cafes and a bustling nightlife scene equipped with endless bars, clubs and live music. There is a little bit of everything offered by the colourful varying squares and districts along the expansive street.

Both metros and buses from the airport route to the nearest Taksim Square, located at the furthest end of the avenue. A tram referred to as the red Nostaljik Tramvay runs up and down the street. Walking is the most popular way of getting around.

Istiklal Avenue serves as a comprehensive architectural exhibition of the Ottoman era boasting buildings across a wide range of styles, from neoclassical through the Renaissance Revival to Art Nouveau.